Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070745 | 1.00 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL22070743 | 1.00 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19816466 | 0.89 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL31196261 | 0.89 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL15308686 | 0.89 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL22796405 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL22816571 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1169921 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6642114 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2485308 | 0.85 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |