Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31196353 | 0.83 | IDO1 (0.51) | CYP2C9IDO1KCNH2KMT2AALDH1A1 | |
| SCHEMBL31196351 | 0.83 | IDO1 (0.51) | CYP2C9IDO1KCNH2KMT2AALDH1A1 | |
| SCHEMBL31196386 | 0.83 | MKNK1 (0.47) | USP2CYP2C9IDO1KCNH2PKM | |
| SCHEMBL31196498 | 0.83 | MKNK1 (0.47) | USP2CYP2C9IDO1KCNH2PKM | |
| SCHEMBL31196606 | 0.82 | IDO1 (0.52) | CYP2C9IDO1KCNH2ALDH1A1TP53 | |
| SCHEMBL18236380 | 0.75 | DRD2 (0.54) | USP2CYP2C9IDO1KCNH2PKM | |
| SCHEMBL17374211 | 0.73 | DRD2 (0.51) | USP2CYP2C9IDO1KCNH2PKM | |
| SCHEMBL17374212 | 0.73 | DRD2 (0.51) | USP2CYP2C9IDO1KCNH2PKM | |
| SCHEMBL432010 | 0.72 | DRD2 (0.65) | USP2PKMKMT2ADRD2SLC6A4 | |
| SCHEMBL31196390 | 0.72 | HTT (0.46) | CYP2C9CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |