⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29583412 | 1.00 | — | — | |
| SCHEMBL7189293 | 0.88 | KMT2A (0.48) | — | |
| SCHEMBL23757065 | 0.76 | KMT2A (0.44) | — | |
| SCHEMBL31619921 | 0.75 | — | — | |
| SCHEMBL971307 | 0.75 | — | — | |
| SCHEMBL670767 | 0.75 | — | — | |
| SCHEMBL12973187 | 0.75 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL17255919 | 0.75 | KMT2A (0.65) | — | |
| SCHEMBL390289 | 0.75 | — | — | |
| SCHEMBL29849628 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402875-A1 | S1P3 Antagonists | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2022-12-22 | — | — | US | claimed |
| CN-109053727-B | Preparation method of ABT-199 intermediate | 山东轩德医药科技有限公司 | 2021-01-26 | — | — | CN | claimed |
| EP-3689864-A1 | S1P3 ANTAGONISTS | Teva Pharmaceutical Industries Limited (IL) | 2020-08-05 | — | — | EP | claimed |
| US-20200157052-A1 | S1P3 Antagonists | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2020-05-21 | — | — | US | claimed |
| CN-111004235-A | Synthetic method of ATX inhibitor Ziritaxestat | 沈阳药科大学 | 2020-04-14 | — | — | CN | claimed |
| CN-110845399-A | Preparation method of 2, 5-dibromo-3-methylpyridine | 常州传侑环保科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110563643-A | synthesis method of (5-bromo-3-methyl-pyridin-2-yl) -methylamine | 常州齐晖药业有限公司 | 2019-12-13 | — | — | CN | claimed |
| EP-3086845-B1 | S1P3 ANTAGONISTS | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2019-11-20 | — | — | EP | claimed |
| CN-109748859-A | A kind of preparation method of the bromo- 3- picoline of 2,5- bis- | 丹阳市易通安全技术服务有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-109053727-A | A kind of preparation method of ABT-199 intermediate | 山东轩德医药科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| WO-2015082357-A1 | S1P3 ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2015-06-11 | — | — | WO | claimed |
| EP-2878339-A1 | SIP3 antagonists | Siena Biotech S.p.A. (IT) | 2015-06-03 | — | — | EP | claimed |
| CN-104387384-A | Synthetic process of 5-bromo-7-azaindole | SHANGHAI HUMAN BIOTECHNOLOGY CO LTD | 2015-03-04 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | claimed |
| CN-1930159-A | Novel dicationic imidazo [1, 2-a ] pyridine and 5,6,7, 8-tetrahydro-imidazo [1, 2-a ] pyridine compounds as antiprotozoal agents | UNIV NORTH CAROLINA (US) | 2007-03-14 | — | — | CN | claimed |
| EP-1745045-A2 | NOVEL DICATIONIC IMIDAZO 1,2-a PYRIDINES AND 5,6,7,8-TE TRAHYDRO-IMIDAZO 1,2a PYRIDINES AS ANTIPROTOZOAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2007-01-24 | — | — | EP | claimed |
| US-20050282853-A1 | Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents | BOYKIN DAVID W | 2005-12-22 | — | — | US | claimed |
| WO-2005086808-A2 | NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-09-22 | — | — | WO | claimed |