⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393219 | 1.00 | — | — | |
| SCHEMBL29426953 | 0.79 | — | — | |
| SCHEMBL1180586 | 0.79 | — | — | |
| SCHEMBL12973187 | 0.79 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL30874142 | 0.79 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL2489172 | 0.79 | — | — | |
| SCHEMBL29845509 | 0.79 | — | — | |
| SCHEMBL23820848 | 0.75 | — | — | |
| SCHEMBL1506656 | 0.75 | — | — | |
| SCHEMBL502626 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217989321-U | Preparation mechanism of 2, 5-dibromo-3-methylpyridine | 靖江市三晶生物科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-110845399-A | Preparation method of 2, 5-dibromo-3-methylpyridine | 常州传侑环保科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110563643-A | synthesis method of (5-bromo-3-methyl-pyridin-2-yl) -methylamine | 常州齐晖药业有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-105348177-A | Preparation method for 2,5-dibromo-3-methylpyridine | FU MINGZHU | 2016-02-24 | — | — | CN | claimed |
| CN-104649966-A | Method for synthesizing organic intermediate 5-cyano-3-methylpyridine formic acid | UNIV EAST CHINA SCIENCE & TECH | 2015-05-27 | — | — | CN | claimed |
| US-20260116884-A1 | PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN) | 2026-04-30 | — | — | US | disclosed |
| US-12528781-B2 | Heterocyclic GLP-1 agonists | GASHERBRUM BIO, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4674484-A2 | THIENOPYRROLE COMPOUNDS | Gilead Sciences, Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4192831-B1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO INC (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4635956-A1 | PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2025-10-22 | — | — | EP | disclosed |
| EP-4291562-B1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |
| WO-1998057958-A1 | SYNTHESIS OF INTERMEDIATES USEFUL IN PREPARING BROMO-SUBSTITUTED TRICYCLIC COMPOUNDS | SCHERING CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |
| WO-1998042676-A1 | SYNTHESIS OF INTERMEDIATES USEFUL IN PREPARING TRICYCLIC COMPOUNDS | SCHERING CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |
| US-5760232-A | Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds | SCHERING CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| US-5760232-A | Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds | SCHERING CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0112707-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H1-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4652650-A | Pyridylaminoalkylamine intermediates | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-24 | — | — | US | disclosed |
| US-4548940-A | Pyridylaminoalkylaminopyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-10-22 | — | — | US | disclosed |
| EP-0112707-A2 | Aminopyrimidinone derivatives as histamine H1-antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-07-04 | — | — | EP | disclosed |