SCHEMBL31196711

SCHEMBL31196711

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 9/20 0.53
▸ NPY4R P50391 9/20 0.53
▸ NPY5R Q15761 9/20 0.53
▸ NPY1R P25929 7/20 0.53
▸ NTSR1 P30989 5/20 0.49
▸ NTSR2 O95665 4/20 0.49
▸ SORT1 Q99523 3/20 0.49
▸ CALCR P30988 4/20 0.48
▸ GRIN2D O15399 1/20 0.46
▸ GRIN3B O60391 1/20 0.46
▸ GRIN1 Q05586 1/20 0.46
▸ GRIN2A Q12879 1/20 0.46
▸ GRIN2B Q13224 1/20 0.46
▸ GRIN2C Q14957 1/20 0.46
▸ GRIN3A Q8TCU5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31196712 0.92 NPY2R (0.53) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL31031595 0.88 NPY2R (0.50) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432890 0.87 NPY2R (0.53) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30512575 0.87 NPY2R (0.49) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL31734555 0.86 NPY2R (0.51) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL29387855 0.86 NPY2R (0.56) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL29662146 0.86 RAMP3 (0.49) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30512731 0.86 NPY2R (0.57) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30512794 0.85 NTSR1 (0.49) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30277901 0.85 NPY2R (0.55) NPY2RNPY4RNPY5RNPY1RNTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705287-A1 SMALL MOLECULE HUMANIN MIMETICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-11 — — EP claimed
WO-2024226731-A1 SMALL MOLECULE HUMANIN MIMETICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-10-31 — — WO claimed
EP-4705287-A1 SMALL MOLECULE HUMANIN MIMETICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-11 — — EP disclosed
WO-2024226731-A1 SMALL MOLECULE HUMANIN MIMETICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-10-31 — — WO disclosed
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