SCHEMBL10032508

SCHEMBL10032508

c1ccc(-c2ccc3ccc4ccc(-c5cccc(-c6ccc7ccc8ccc(-c9ccccc9)nc8c7n6)c5)cc4c3n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.45
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
RAB9A P51151 1/20 0.44
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ASIC3 Q9UHC3 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
GLA P06280 1/20 0.37
PIM1 P11309 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
ALK Q9UM73 1/20 0.36
PLG P00747 1/20 0.36
PLAU P00749 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21674508 1.00 PARP1 (0.45) PARP1MEN1KMT2ARAB9ACYP1A1
SCHEMBL10032321 0.95 PARP1 (0.43) PARP1MEN1KMT2ARAB9APLG
SCHEMBL31198218 0.95 PARP1 (0.43) PARP1MEN1KMT2ARAB9APLG
SCHEMBL10032361 0.95 PARP1 (0.43) PARP1MEN1KMT2ARAB9APLG
SCHEMBL10032456 0.95 PARP1 (0.43) PARP1MEN1KMT2ARAB9APLG
SCHEMBL10032348 0.95 PARP1 (0.43) PARP1MEN1KMT2ARAB9APLG
SCHEMBL10032355 0.95 PARP1 (0.46) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL10032457 0.95 PARP1 (0.46) PARP1MEN1KMT2ARAB9AASIC3
SCHEMBL10032345 0.91 PARP1 (0.45) PARP1MEN1KMT2ARAB9ACYP1A1
SCHEMBL10032418 0.91 PARP1 (0.45) PARP1MEN1KMT2ARAB9ACYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200243773-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-07-30 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200243773-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, L1CAM, EML4 PARP1 1635/4885MEN1 1002/4885KMT2A 2240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.