Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198253 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL30593632 | 0.84 | CHRNA3 (0.45) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL30593635 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRCHRNA3KMT2AMEN1 | |
| SCHEMBL31198244 | 0.81 | CHRNA3 (0.48) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL29965119 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRCHRNA3KMT2AMEN1 | |
| SCHEMBL30628898 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL12467310 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL30628897 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCHRNA3KMT2AHTT | |
| SCHEMBL29965066 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRKMT2AMEN1HSD17B10 | |
| SCHEMBL31198250 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRCHRNA3KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118871116-A | Compounds for the treatment of cancer | 卡希夫生物科学有限公司 | 2024-10-29 | — | — | CN | disclosed |