Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198964 | 0.98 | — | — | |
| SCHEMBL31358067 | 0.83 | — | — | |
| SCHEMBL31198884 | 0.76 | CHEK1 (0.34) | — | |
| SCHEMBL31198869 | 0.72 | ERBB2 (0.33) | — | |
| SCHEMBL31331228 | 0.69 | — | — | |
| SCHEMBL31513029 | 0.69 | GPR17 (0.33) | — | |
| SCHEMBL22531920 | 0.69 | GPR17 (0.33) | — | |
| SCHEMBL20764903 | 0.69 | HTR1A (0.35) | — | |
| SCHEMBL25293238 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL425657 | 0.66 | PDPK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |