Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.35 |
| ▸ | SKP1 | P63208 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198986 | 0.91 | BTK (0.43) | BTKPROKR1CYP11B2GPR119HPGDS | |
| SCHEMBL20661329 | 0.86 | BTK (0.51) | BTKPROKR1CYP11B2GPR119CKS1B | |
| SCHEMBL20448598 | 0.82 | BTK (0.44) | BTKPROKR1CYP11B2GPR119 | |
| SCHEMBL31555855 | 0.81 | BTK (0.47) | BTKPROKR1GPR119USP30 | |
| SCHEMBL25231247 | 0.81 | GBA1 (0.49) | BTKCYP11B2GPR119CKS1BSKP1 | |
| SCHEMBL31198941 | 0.79 | BTK (0.41) | BTKGPR119 | |
| SCHEMBL22778172 | 0.79 | BTK (0.42) | BTKCYP11B2GPR119 | |
| SCHEMBL29468038 | 0.79 | BTK (0.42) | BTKCYP11B2GPR119 | |
| SCHEMBL2882626 | 0.78 | NAMPT (0.54) | BTKCYP11B2 | |
| SCHEMBL17530336 | 0.77 | GPR119 (0.48) | BTKGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |