Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943672 | 0.88 | KDM4E (0.37) | RAB9AKMT2AMEN1HDAC4HDAC6 | |
| SCHEMBL25964997 | 0.84 | RARB (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL31083780 | 0.84 | RARB (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL21896456 | 0.84 | RARB (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL17721291 | 0.84 | RARB (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL16974355 | 0.83 | TP53 (0.40) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL25913003 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2HDAC3HDAC1NPC1RAB9A | |
| SCHEMBL18384364 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2HDAC3HDAC1NPC1RAB9A | |
| SCHEMBL25913000 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2HDAC3HDAC1NPC1RAB9A | |
| SCHEMBL30326680 | 0.80 | TP53 (0.35) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233966-A2 | MODULATING STROMAL AND IMMUNE CELLS IN ATRIAL DISEASE | THE GENERAL HOSPITAL CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |