Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17615144 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2CA2HDAC1HDAC3MEN1 | |
| SCHEMBL14727910 | 0.83 | MEN1 (0.36) | SMN1; SMN2HDAC1MEN1KMT2AEPHX2 | |
| SCHEMBL23280517 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2CA2HDAC1HDAC3MEN1 | |
| SCHEMBL15646002 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2CA2KMT2AEPHX2NR1H4 | |
| SCHEMBL31199169 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2CA2HDAC1HDAC3MEN1 | |
| SCHEMBL13056381 | 0.79 | ADORA3 (0.43) | SMN1; SMN2HDAC1HDAC3EPHX2NPC1 | |
| SCHEMBL26040572 | 0.78 | HPGD (0.31) | SMN1; SMN2HPGDHTT | |
| SCHEMBL19001602 | 0.78 | PYGL (0.36) | SMN1; SMN2MEN1KMT2AHPGDHTT | |
| SCHEMBL28693018 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CA2HDAC1HDAC3KMT2A | |
| SCHEMBL28600185 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015710-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015710-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | VIP, NGLY1, GRPR | SMN1; SMN2 3403/4885CA2 3904/4885HDAC1 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.