Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31200493 | 0.88 | RAB9A (0.56) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL25199236 | 0.87 | NPC1 (0.68) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL25197014 | 0.87 | NPC1 (0.68) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL31200539 | 0.86 | RAB9A (0.53) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL24071510 | 0.86 | NPC1 (0.67) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL24071501 | 0.84 | NPC1 (0.70) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL24071507 | 0.84 | NPC1 (0.67) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL24071512 | 0.82 | NPC1 (0.61) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL24071505 | 0.81 | NPC1 (0.63) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL24071962 | 0.80 | RAB9A (0.88) | NPC1RAB9AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233501-A2 | THERAPEUTIC COMPOUNDS | ALLOROCK, INC. (US) | 2024-11-14 | — | — | WO | disclosed |