Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 13/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 0.46 |
| ▸ | CDK2 | P24941 | 11/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.39 |
| ▸ | CDK9 | P50750 | 11/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 11/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 11/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 10/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201166 | 0.94 | GABRA1 (0.41) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201113 | 0.85 | DYRK1A (0.41) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201383 | 0.82 | GABRA1 (0.36) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201386 | 0.82 | GABRA1 (0.33) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201375 | 0.81 | CDK7 (0.53) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201227 | 0.81 | CDK7 (0.53) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201240 | 0.81 | CCNA2 (0.39) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201150 | 0.80 | TYK2 (0.36) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201130 | 0.80 | CCNA2 (0.33) | DYRK1ACDK5CDK5R1CDK2CCNA2 | |
| SCHEMBL31201350 | 0.78 | GABRA1 (0.33) | DYRK1ACDK5CDK5R1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | claimed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | claimed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |