Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 9/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 9/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159353 | 0.75 | SMN1; SMN2 (0.57) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11423133 | 0.75 | MAPT (0.58) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29977842 | 0.73 | MAPT (0.56) | EEDMAPTKDM4EALDH1A1 | |
| SCHEMBL31201352 | 0.71 | GRIN2D (0.40) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20860985 | 0.71 | GRIN2D (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3034000 | 0.71 | GRIN2D (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24604195 | 0.70 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30109411 | 0.70 | MAPT (0.53) | MAPTKDM4EALDH1A1 | |
| SCHEMBL2646178 | 0.70 | CYP1A2 (0.48) | MAPTKDM4EALDH1A1 | |
| SCHEMBL30893809 | 0.70 | CYP1A2 (0.48) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |