Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 11/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.38 |
| ▸ | EED | O75530 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201511 | 0.92 | ALDH1A1 (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31201233 | 0.80 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31201288 | 0.71 | GABRA1 (0.33) | ADRA1A | |
| SCHEMBL31201546 | 0.71 | EED (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31201514 | 0.68 | GABRA1 (0.35) | — | |
| SCHEMBL31201417 | 0.68 | FADS1 (0.42) | MAPT | |
| SCHEMBL31201490 | 0.66 | TDP1 (0.33) | — | |
| SCHEMBL31201523 | 0.66 | GABRA1 (0.36) | MAPT | |
| SCHEMBL6159353 | 0.65 | SMN1; SMN2 (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11423133 | 0.65 | MAPT (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |