SCHEMBL31202244

SCHEMBL31202244

O=C(Cn1nc(C2CCC(=O)NC2=O)c2ccccc21)NCC1(O)CC1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 17/20 0.54
CRBN Q96SW2 17/20 0.54
CHRNA7 P36544 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31202304 0.87 DDB1 (0.56) DDB1CRBNCHRNA7
SCHEMBL31202341 0.85 DDB1 (0.59) DDB1CRBNCHRNA7
SCHEMBL31202228 0.85 DDB1 (0.57) DDB1CRBN
SCHEMBL31202219 0.85 DDB1 (0.54) DDB1CRBNCHRNA7
SCHEMBL31202079 0.85 DDB1 (0.57) DDB1CRBN
SCHEMBL31202248 0.84 DDB1 (0.56) DDB1CRBNCHRNA7
SCHEMBL24669902 0.84 DDB1 (0.65) DDB1CRBN
SCHEMBL31201973 0.83 DDB1 (0.57) DDB1CRBNCHRNA7
SCHEMBL31202077 0.83 DDB1 (0.56) DDB1CRBNCHRNA7
SCHEMBL31202121 0.82 DDB1 (0.53) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368114-A1 INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX INC (US) 2024-11-07 US claimed
US-20240368114-A1 INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX INC (US) 2024-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368114-A1 INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CSNK1G3, CSNK1A1, CSNK1D DDB1 3279/4885CRBN 2500/4885CHRNA7 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.