CSNK1G3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1043587	0.77	4/20
SCHEMBL1046067	0.72	4/20
SCHEMBL1043445	0.67	4/20
SCHEMBL1043448	0.67	4/20
SCHEMBL1045877	0.65	4/20
SCHEMBL1045231	0.63	4/20
SCHEMBL1045663	0.62	4/20
SCHEMBL1044969	0.60	4/20
SCHEMBL1046432	0.59	4/20
SCHEMBL420484	0.59	4/20
SCHEMBL1044761	0.58	4/20
SCHEMBL1041773	0.56	4/20
SCHEMBL1046029	0.55	4/20
SCHEMBL1045731	0.51	4/20
SCHEMBL1046261	0.50	4/20
SCHEMBL232042	1.00	3/20
Bi-2536 (SCHEMBL372489)	1.00	3/20
A-443654 (SCHEMBL570604)	1.00	3/20
Bi-2536 (SCHEMBL614114)	1.00	3/20
SCHEMBL376821	0.90	3/20

Clinical trials — most relevant to CSNK1G3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus	PHASE3	UNKNOWN
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome	PHASE3	COMPLETED
Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy	PHASE2	COMPLETED
Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus	PHASE1/PHASE2	WITHDRAWN
Doxycycline in Human Pulmonary Tuberculosis	PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Bristol-Myers Squibb Dasatinib Src Inhibition in Endometrial Cancer	EARLY_PHASE1	COMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Identification of Novel Targetable Kinases in SR-a GvHD	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex	nan	COMPLETED
Study of Metabolic Modifications in Children With Noonan Syndrome	nan	COMPLETED
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Determining the Association of Chromosomal Variants With Non-PV Triggers and Ablation-outcome in AF (DECAF)	nan	COMPLETED
Genetic Markers of CHD Risk in Men and Women	nan	COMPLETED
JAK-STAT Signalling Pathway in Familial Myeloproliferative Disorders	nan	COMPLETED
Exploring the Genetics of Neuropathic Pain	nan	RECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration	nan	UNKNOWN
Genetic Studies of Inflammatory Bowel Disease	nan	COMPLETED
Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease	nan	UNKNOWN
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease	nan	COMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
IPSC Repository of Pediatric Cardiovascular Disease	nan	RECRUITING
Ischemic Preconditioning to Prevent Acute Kidney Injury	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
PCM1-JAK2 in Therapy Related Neoplasms	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CSNK1G3 binder may also engage these)

Protein	Name	Similarity
Q8BTH8	—	1.000	Q8BTH8 →
Q5R4V3	—	1.000	Q5R4V3 →
Q62763	—	1.000	Q62763 →
Q8BVP5	—	0.999	Q8BVP5 →
Q8C4X2	—	0.999	Q8C4X2 →
Q5ZJS0	—	0.997	Q5ZJS0 →
Q62762	—	0.997	Q62762 →
Q6NRT0	—	0.996	Q6NRT0 →
CSNK1G2	Casein kinase I isoform gamma-2	0.996	landscape →
Q5PRD4	—	0.995	Q5PRD4 →
A7E3X2	—	0.993	A7E3X2 →
CSNK1G1	Casein kinase I isoform gamma-1	0.993	landscape →
Q39050	—	0.992	Q39050 →
Q62761	—	0.990	Q62761 →
Q9ZUP4	—	0.989	Q9ZUP4 →
Q93Z18	—	0.988	Q93Z18 →
Q4R9A9	—	0.988	Q4R9A9 →
A0A0J9UVX2	—	0.987	A0A0J9UVX2 →
G4MYB0	—	0.986	G4MYB0 →
P40233	—	0.986	P40233 →
CSNK1E	Casein kinase I isoform epsilon	0.985	landscape →
I1S050	—	0.985	I1S050 →
P40236	—	0.985	P40236 →
P40234	—	0.985	P40234 →
Q5ZLL1	—	0.984	Q5ZLL1 →
Q6K9N1	—	0.984	Q6K9N1 →
Q6P3K7	—	0.984	Q6P3K7 →
Q5RC72	—	0.984	Q5RC72 →
P42158	—	0.983	P42158 →
Q8WQ99	—	0.982	Q8WQ99 →