Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105122 | 1.00 | PARG (0.43) | PARGPTGDR2MEN1ALOX15MAPK1 | |
| SCHEMBL30602786 | 0.89 | PTGDR2 (0.40) | PARGPTGDR2PTGER4FSCN1NPBWR1 | |
| SCHEMBL26108490 | 0.86 | CNR2 (0.47) | PARGKMT2A | |
| SCHEMBL26108569 | 0.84 | MEN1 (0.41) | PARGMEN1ALOX15MAPK1KMT2A | |
| SCHEMBL31202607 | 0.84 | MEN1 (0.41) | PARGMEN1ALOX15MAPK1KMT2A | |
| SCHEMBL30602808 | 0.79 | CNR1 (0.40) | PTGER4FSCN1NPBWR1PIK3CA | |
| SCHEMBL30602806 | 0.74 | CNR2 (0.50) | PTGDR2 | |
| SCHEMBL31202705 | 0.73 | TEAD1 (0.39) | PARGMEN1ALOX15MAPK1KMT2A | |
| SCHEMBL26107184 | 0.73 | TEAD1 (0.39) | PARGMEN1ALOX15MAPK1KMT2A | |
| SCHEMBL30602780 | 0.73 | CNR1 (0.44) | PTGDR2PTGER4NPBWR1PPARAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |