Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EPHB3 | P54753 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757240 | 0.87 | EPHB3 (0.42) | ALDH1A1KDM4EHSD17B10EPHB3GAA | |
| SCHEMBL31205187 | 0.83 | DRD2 (0.48) | ALDH1A1TSHRKMT2ALMNAHPGD | |
| SCHEMBL28801140 | 0.81 | EPHB3 (0.43) | KDM4EEPHB3NOTUML3MBTL1KMT2A | |
| SCHEMBL31204928 | 0.76 | GAA (0.38) | ALDH1A1KDM4EHSD17B10EPHB3GAA | |
| SCHEMBL31205407 | 0.76 | GAA (0.38) | ALDH1A1KDM4EHSD17B10EPHB3GAA | |
| SCHEMBL31204952 | 0.76 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1KMT2A | |
| SCHEMBL25757242 | 0.75 | DRD4 (0.39) | ALDH1A1KDM4EHSD17B10EPHB3GAA | |
| SCHEMBL28801157 | 0.74 | EPHB3 (0.39) | ALDH1A1KDM4EHSD17B10EPHB3L3MBTL1 | |
| SCHEMBL25757792 | 0.74 | ATR (0.35) | ALDH1A1KDM4EHSD17B10EPHB3KMT2A | |
| SCHEMBL21816279 | 0.74 | IRAK4 (0.47) | ALDH1A1KDM4EHSD17B10EPHB3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727941-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024255164-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024254834-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024255885-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |