Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | ELANE | P08246 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122010 | 0.85 | MAPT (0.58) | MAPTMAPK1ELANEKDM4ELMNA | |
| SCHEMBL3113752 | 0.85 | HPGD (0.68) | MAPTMAPK1ELANEKDM4ELMNA | |
| SCHEMBL4622496 | 0.82 | MAPT (0.66) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL11316893 | 0.79 | MAPK1 (0.67) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL13133207 | 0.79 | MAPT (0.79) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL29050458 | 0.79 | MAPK1 (0.61) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL10483738 | 0.78 | ELANE (1.00) | MAPTMAPK1ELANE | |
| SCHEMBL9211658 | 0.78 | MAPT (0.68) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL6534743 | 0.77 | MAPK1 (0.59) | MAPTMAPK1ELANEKDM4EPOLB | |
| SCHEMBL28810896 | 0.77 | MAPT (0.59) | MAPTMAPK1ELANEKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732645-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-2161248-A1 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7518021-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | IWAHAMA TAKAHIRO | 2009-04-02 | — | — | US | disclosed |
| US-20040181098-A1 | Aromatic vinyl ether compounds | EMORY UNIVERSITY | 2004-09-16 | — | — | US | disclosed |
| EP-1413568-A2 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181098-A1 | Aromatic vinyl ether compounds | SUV39H2, SUV39H1, RAVER1 | MAPT 2131/4885MAPK1 2088/4885ELANE 2856/4885 |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | SUV39H2, SUV39H1, RAVER1 | MAPT 2199/4885MAPK1 3015/4885ELANE 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.