Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206960 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31206999 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207091 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207076 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207080 | 0.81 | RAB9A (0.70) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207181 | 0.80 | MEN1 (0.57) | SMN1; SMN2HTTRAB9ANPC1CCNE1 | |
| SCHEMBL265456 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207079 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31207120 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTRAB9ANPC1PKM | |
| SCHEMBL31206965 | 0.74 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTRAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955493-A | Novel CCNK molecular gel degradation agent, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-11-15 | — | — | CN | disclosed |