Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15671563 | 1.00 | TSHR (0.53) | TSHRL3MBTL1MAPTGAATDP1 | |
| SCHEMBL29835091 | 0.89 | TSHR (0.45) | TSHRL3MBTL1MAPTGAATDP1 | |
| SCHEMBL29686473 | 0.85 | TSHR (0.54) | TSHRL3MBTL1MAPTGAATDP1 | |
| SCHEMBL521662 | 0.85 | TSHR (0.68) | TSHRL3MBTL1MAPTGAATDP1 | |
| SCHEMBL7111424 | 0.85 | TSHR (0.54) | TSHRL3MBTL1MAPTGAATDP1 | |
| SCHEMBL1126945 | 0.84 | TSHR (0.53) | TSHRL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL18929981 | 0.84 | TSHR (0.45) | TSHRL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL11693993 | 0.84 | TSHR (0.53) | TSHRL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL16957718 | 0.83 | TSHR (0.51) | TSHRL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL15689544 | 0.83 | CTSD (0.65) | TSHRL3MBTL1ALDH1A1HTTCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724752-A | Tyrosine kinase inhibitor intermediate, preparation method and application thereof | 重庆博腾制药科技股份有限公司 | 2024-10-01 | — | — | CN | disclosed |