Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630647 | 1.00 | ACP1 (0.47) | ACP1HRH3MCHR1CHRM1HTR2A | |
| SCHEMBL21589940 | 0.85 | ACP1 (0.47) | ACP1HRH3MCHR1CHRM1HTR2A | |
| SCHEMBL29922075 | 0.81 | MAOB (0.54) | ACP1HRH3MCHR1CHRM1HTR2A | |
| SCHEMBL23630643 | 0.81 | MAOB (0.54) | ACP1HRH3MCHR1CHRM1HTR2A | |
| SCHEMBL31207324 | 0.78 | MELK (0.45) | ACP1HRH3TAAR1MELK | |
| SCHEMBL23630642 | 0.78 | MELK (0.45) | ACP1HRH3TAAR1MELK | |
| SCHEMBL23630646 | 0.77 | HRH3 (0.46) | ACP1HRH3TAAR1MELK | |
| SCHEMBL31207322 | 0.77 | HRH3 (0.46) | ACP1HRH3TAAR1MELK | |
| SCHEMBL26798799 | 0.75 | NOS3 (0.46) | HTR2ABACE1MAPTABL1ABCB1 | |
| SCHEMBL25365883 | 0.74 | ABL1 (0.44) | BACE1NPC1MAPK1RAB9AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802492-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF DISORDERS ASSOCIATED WITH MUTANT RAS | THE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL (GB) | 2024-11-06 | — | — | EP | claimed |