Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 2/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207410 | 0.82 | STIM1 (0.39) | STIM1ORAI1DGAT1GRM5KCNH2 | |
| SCHEMBL26461251 | 0.82 | STIM1 (0.38) | STIM1ORAI1BACE1GRM5KCNH2 | |
| SCHEMBL31207488 | 0.82 | STIM1 (0.38) | STIM1ORAI1BACE1GRM5KCNH2 | |
| SCHEMBL30296156 | 0.82 | STIM1 (0.38) | STIM1ORAI1BACE1GRM5KCNH2 | |
| SCHEMBL31207452 | 0.82 | STIM1 (0.38) | STIM1ORAI1BACE1GRM5KCNH2 | |
| SCHEMBL30296556 | 0.82 | PIK3CA (0.43) | STIM1ORAI1GRM5PRKAG1PRKAA1 | |
| SCHEMBL26458701 | 0.82 | PIK3CA (0.43) | STIM1ORAI1GRM5PRKAG1PRKAA1 | |
| SCHEMBL30296439 | 0.81 | PIK3CD (0.39) | STIM1ORAI1GRM5PRKAG1PRKAA1 | |
| SCHEMBL26459791 | 0.81 | PIK3CD (0.39) | STIM1ORAI1GRM5PRKAG1PRKAA1 | |
| SCHEMBL30296510 | 0.80 | WDR5 (0.43) | STIM1ORAI1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |