Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 6/20 | 0.45 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | PAICS | P22234 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296663 | 0.90 | TDO2 (0.45) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL26461154 | 0.88 | TDO2 (0.43) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL30296462 | 0.88 | TDO2 (0.43) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL30296607 | 0.88 | TDO2 (0.43) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL30296565 | 0.85 | TDO2 (0.41) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL31207378 | 0.85 | ALOX5AP (0.45) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL30296242 | 0.82 | TDO2 (0.38) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL30296497 | 0.82 | TDO2 (0.38) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL26459805 | 0.82 | TDO2 (0.38) | FEN1TDO2PAICSALOX5APDGAT1 | |
| SCHEMBL26459487 | 0.82 | TDO2 (0.38) | FEN1TDO2PAICSALOX5APDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |