Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296178 | 0.82 | PTPN11 (0.42) | PTPN11TDO2MEN1MAPTKMT2A | |
| SCHEMBL15690403 | 0.71 | PTPN11 (0.56) | PTPN11MEN1MAPTKMT2AAPAF1 | |
| SCHEMBL12302731 | 0.71 | CCNC (0.40) | TDO2MAP4K4 | |
| SCHEMBL31207423 | 0.71 | CYP2A6 (0.51) | TDO2ABL1PTGS2 | |
| SCHEMBL5244458 | 0.69 | PTGS2 (0.42) | TDO2MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28481934 | 0.69 | MAPT (0.40) | MAPTAPAF1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3858998 | 0.69 | PTPN11 (0.58) | PTPN11TDO2MEN1MAPTKMT2A | |
| SCHEMBL3729841 | 0.66 | KDM1A (0.51) | TDO2MAPTKMT2AALDH1A1BACE1 | |
| SCHEMBL27884914 | 0.65 | USP7 (0.43) | ALDH1A1THRBRECQLABL1TSHR | |
| SCHEMBL13933744 | 0.64 | HDAC1 (0.33) | MAPTMAPK14ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |