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SCHEMBL31208124

SCHEMBL31208124

CCCN(CC1CCN(C(=O)c2cccc(C(N)=O)c2)CC1)C1CCc2c(O)cccc2C1

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 7/20 0.59
▸ DRD3 P35462 7/20 0.59
▸ DRD4 P21917 3/20 0.57
▸ HTR1A P08908 1/20 0.57
▸ DRD1 P21728 1/20 0.57
▸ DRD5 P21918 1/20 0.57
▸ HTR7 P34969 1/20 0.57
▸ ADRB2 P07550 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31208109 1.00 DRD2 (0.59) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208089 1.00 DRD2 (0.59) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208087 0.89 DRD2 (0.57) DRD2DRD3DRD4HTR1A
SCHEMBL31208084 0.89 DRD2 (0.57) DRD2DRD3DRD4HTR1A
SCHEMBL31208107 0.89 DRD2 (0.57) DRD2DRD3DRD4HTR1A
SCHEMBL31208120 0.86 DRD2 (0.57) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208096 0.85 DRD2 (0.56) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208118 0.85 DRD2 (0.57) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208097 0.85 DRD2 (0.72) DRD2DRD3DRD4HTR1ADRD1
SCHEMBL31208088 0.83 DRD2 (0.59) DRD2DRD3DRD4HTR1ADRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024222837-A1 TETRAHYDRONAPHTHYLPROPYLAMINOMETHYLPIPERIDINE ARYL (SULFONYL)AMIDE DERIVATIVE, PREPARATION METHOD, AND APPLICATION THEREOF 江苏恩华药业股份有限公司 2024-10-31 — — WO disclosed