Validamycin

Validamycin

SCHEMBL3121491

OCC1=C[C@H](N[C@H]2C[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ AMY2A P04746 8/20 0.56
▸ MGAM O43451 6/20 0.56
▸ SI P14410 5/20 0.56
▸ GAA P10253 4/20 0.56
▸ AMY1A P0DUB6 3/20 0.56
▸ CNR1 P21554 1/20 0.56
▸ PTGS1 P23219 1/20 0.56
▸ PDE4A P27815 1/20 0.56
▸ PDE3A Q14432 1/20 0.56
▸ MGAM2 Q2M2H8 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ GLA P06280 1/20 0.56
▸ TREH O43280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Validamycin A SCHEMBL29451180 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL15906030 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL10033386 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14408718 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14408710 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL8819801 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL16028080 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL19231832 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14409005 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL12347612 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 — — EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 — — EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 — — EP claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 — — WO claimed
WO-2025217346-A1 COMPOSITIONS AND METHODS FOR CROP-PROTECTION AND USES THEREOF TIDAL VISION PRODUCTS (US) 2025-10-16 — — WO claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 — — EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 — — EP claimed
CN-120036142-A High-altitude layering propagation method for dalbergia odorifera and application of high-altitude layering propagation method 中国医学科学院药用植物研究所海南分所 2025-05-27 — — CN claimed
WO-2025092438-A1 NICOTINIC ACID ESTER COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-05-08 — — WO claimed
WO-2025000181-A1 GOSSYPOL-CONTAINING STEM BORER-KILLING COMPOSITION 山东省农业科学院 2025-01-02 — — WO claimed
CN-104754943-A Active compound combinations BAYER CROPSCIENCE AG 2015-07-01 — — CN claimed
CN-104754940-A Active compound combinations BAYER CROPSCIENCE AG 2015-07-01 — — CN claimed
WO-2014037315-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-03-13 — — WO claimed
WO-2014037314-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-03-13 — — WO claimed
CN-103635089-A Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound BAYER IP GMBH 2014-03-12 — — CN claimed
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-06 — — US claimed
EP-2515649-A2 ACTIVE COMPOUND COMBINATIONS Bayer Intellectual Property GmbH (DE) 2012-10-31 — — EP claimed
EP-2398326-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2011-12-28 — — EP claimed
WO-2010094728-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2010-08-26 — — WO claimed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND AADAC, TUBA3C, NAT1 AMY2A 3204/4885MGAM 71/4885SI 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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