Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162628 | 0.86 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19813985 | 0.84 | L3MBTL1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21713467 | 0.82 | L3MBTL1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31133273 | 0.81 | GAA (0.41) | TSHRLMNAGAAKDM4EL3MBTL1 | |
| SCHEMBL22674555 | 0.81 | KDM4E (0.51) | TSHRGAAKDM4EL3MBTL1POLB | |
| SCHEMBL23214285 | 0.81 | GAA (0.41) | TSHRLMNAGAAKDM4EL3MBTL1 | |
| SCHEMBL2025343 | 0.81 | SOS1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19278157 | 0.81 | TSHR (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30390198 | 0.81 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29767601 | 0.81 | KDM4E (0.51) | TSHRGAAKDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208256-A1 | TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-10-10 | — | — | WO | disclosed |