Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378560 | 0.91 | GAA (0.49) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL3681759 | 0.86 | LCK (0.47) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL30337032 | 0.86 | LCK (0.47) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL31301254 | 0.84 | GAA (0.49) | GAASOS1ABL1HTTKMT2A | |
| SCHEMBL197110 | 0.83 | SOS1 (0.50) | GAASOS1ABL1MAPTKMT2A | |
| SCHEMBL16869865 | 0.83 | LCK (0.51) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL26519870 | 0.81 | KMT2A (0.52) | GAAMAPTNPSR1KMT2AHPGD | |
| SCHEMBL3689533 | 0.81 | GAA (0.46) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL17118715 | 0.80 | MAPT (0.47) | GAASOS1ABL1HTTMAPT | |
| SCHEMBL31487952 | 0.80 | MAPT (0.47) | GAASOS1ABL1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143719-A | Preparation method of LH-1801 key intermediate | 扬州市普林斯医药科技有限公司 | 2024-12-17 | — | — | CN | disclosed |