SCHEMBL31218844

SCHEMBL31218844

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(CCOCC(=O)OC(C)(C)C)cc21

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 20/20 0.58
▸ CRBN Q96SW2 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26099178 0.98 DDB1 (0.57) DDB1CRBN
SCHEMBL26102145 0.98 DDB1 (0.57) DDB1CRBN
SCHEMBL22526137 0.96 DDB1 (0.58) DDB1CRBN
SCHEMBL21069358 0.94 DDB1 (0.56) DDB1CRBN
SCHEMBL21071113 0.94 DDB1 (0.56) DDB1CRBN
SCHEMBL22502475 0.94 DDB1 (0.56) DDB1CRBN
SCHEMBL31218908 0.91 CRBN (0.52) DDB1CRBN
SCHEMBL29651793 0.89 CRBN (0.62) DDB1CRBN
SCHEMBL22526656 0.89 CRBN (0.62) DDB1CRBN
SCHEMBL31218774 0.88 CRBN (0.63) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119013277-A TYK2 degrading agent and application thereof 凯麦拉医疗公司 2024-11-22 — — CN disclosed
Send feedback