Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099178 | 0.92 | DDB1 (0.57) | CRBNDDB1 | |
| SCHEMBL26102145 | 0.92 | DDB1 (0.57) | CRBNDDB1 | |
| SCHEMBL31218844 | 0.91 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL21071113 | 0.88 | DDB1 (0.56) | CRBNDDB1TRIM24 | |
| SCHEMBL22502475 | 0.88 | DDB1 (0.56) | CRBNDDB1TRIM24 | |
| SCHEMBL21069358 | 0.88 | DDB1 (0.56) | CRBNDDB1TRIM24 | |
| SCHEMBL22526137 | 0.86 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL26098420 | 0.85 | CRBN (0.61) | CRBNDDB1TRIM24GSPT1 | |
| SCHEMBL26102516 | 0.85 | CRBN (0.61) | CRBNDDB1TRIM24GSPT1 | |
| SCHEMBL21070678 | 0.84 | CRBN (0.57) | CRBNDDB1GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |