SCHEMBL31218900

SCHEMBL31218900

CNc1cc(Nc2cccc(-c3ncccc3C(=O)O)c2OC)nn2c(C(=O)N[C@@H]3C[C@@H]3F)cnc12

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYK2 P29597 20/20 0.58
▸ PDE4D Q08499 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392474 0.85 TYK2 (0.58) TYK2PDE4D
SCHEMBL30392636 0.85 TYK2 (0.56) TYK2PDE4D
SCHEMBL26099511 0.85 TYK2 (0.56) TYK2PDE4D
SCHEMBL26100797 0.84 TYK2 (0.68) TYK2PDE4D
SCHEMBL30392750 0.81 TYK2 (0.66) TYK2PDE4D
SCHEMBL26102149 0.81 TYK2 (0.55) TYK2PDE4D
SCHEMBL30392650 0.80 TYK2 (0.48) TYK2PDE4D
SCHEMBL26101299 0.80 TYK2 (0.48) TYK2PDE4D
SCHEMBL26102106 0.79 TYK2 (0.56) TYK2PDE4D
SCHEMBL21571880 0.79 TYK2 (0.73) TYK2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119013277-A TYK2 degrading agent and application thereof 凯麦拉医疗公司 2024-11-22 — — CN disclosed
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