Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824679 | 0.81 | PARP1 (0.44) | PARP1FPR2FPR3GPR119NR1H2 | |
| SCHEMBL27904548 | 0.81 | PARP1 (0.46) | PARP1NR1H2NR1H3CA1CA2 | |
| SCHEMBL873250 | 0.81 | PARP1 (0.46) | PARP1NR1H2NR1H3CA1CA2 | |
| SCHEMBL5796411 | 0.79 | PARP1 (0.48) | PARP1NR1H2NR1H3MC4RMC5R | |
| SCHEMBL4710881 | 0.78 | PARP1 (0.48) | PARP1NR1H2NR1H3CA1CA2 | |
| SCHEMBL7460398 | 0.78 | PARP1 (0.48) | PARP1GPR119NR1H2NR1H3ATM | |
| SCHEMBL8575126 | 0.78 | PARP1 (0.48) | PARP1GPR119NR1H2NR1H3ATM | |
| SCHEMBL31218759 | 0.77 | PARP1 (0.52) | PARP1NR1H2NR1H3ATMCA1 | |
| SCHEMBL5224956 | 0.75 | PARP1 (0.50) | PARP1KMT2AALDH1A1ATMCA1 | |
| SCHEMBL5224952 | 0.75 | PARP1 (0.50) | PARP1KMT2AALDH1A1ATMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |