Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | TEK | Q02763 | 4/20 | 0.39 |
| ▸ | SRC | P12931 | 15/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219412 | 0.91 | SRC (0.38) | LCKKDRTEKSRCBTK | |
| SCHEMBL31219403 | 0.86 | SRC (0.40) | LCKKDRTEKSRCBTK | |
| SCHEMBL26105238 | 0.82 | SRC (0.43) | LCKKDRTEKSRCBTK | |
| SCHEMBL30582582 | 0.82 | SRC (0.43) | LCKKDRTEKSRCBTK | |
| SCHEMBL22659216 | 0.81 | SRC (0.53) | LCKKDRTEKSRCBTK | |
| SCHEMBL31219400 | 0.78 | LCK (0.42) | LCKKDRTEKSRCBTK | |
| SCHEMBL31219381 | 0.78 | SRC (0.45) | LCKKDRTEKSRCBTK | |
| SCHEMBL30582573 | 0.75 | SRC (0.40) | LCKKDRTEKSRCBTK | |
| SCHEMBL26105368 | 0.75 | SRC (0.40) | LCKKDRTEKSRCBTK | |
| SCHEMBL30582598 | 0.74 | SRC (0.40) | KDRSRCBTKEGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |