Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 12/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105238 | 1.00 | SRC (0.43) | SRCEGFRBTKABL1ABL2 | |
| SCHEMBL30582500 | 0.87 | BTK (0.55) | EGFRBTKKCNH2RET | |
| SCHEMBL22659216 | 0.87 | SRC (0.53) | SRCEGFRBTKABL1ABL2 | |
| SCHEMBL26105368 | 0.82 | SRC (0.40) | SRCEGFRBTKABL1ABL2 | |
| SCHEMBL30582573 | 0.82 | SRC (0.40) | SRCEGFRBTKABL1ABL2 | |
| SCHEMBL30582591 | 0.82 | LCK (0.42) | SRCEGFRBTKABL1KDR | |
| SCHEMBL26108281 | 0.82 | LCK (0.42) | SRCEGFRBTKABL1KDR | |
| SCHEMBL31219422 | 0.82 | LCK (0.39) | SRCEGFRBTKABL1ABL2 | |
| SCHEMBL26113306 | 0.81 | BTK (0.40) | EGFRBTKKCNH2KDRLCK | |
| SCHEMBL30582598 | 0.80 | SRC (0.40) | SRCEGFRBTKABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |