Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499896 | 0.87 | LMNA (0.48) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL31220147 | 0.85 | MEN1 (0.46) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL5497405 | 0.83 | MAPT (0.48) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL31219731 | 0.83 | MEN1 (0.44) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL1613300 | 0.81 | MEN1 (0.40) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL13825600 | 0.81 | AKR1B1 (0.43) | MEN1KMT2AGAATP53ALDH1A1 | |
| SCHEMBL2242471 | 0.81 | MEN1 (0.45) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL25805362 | 0.81 | AKR1B1 (0.43) | MEN1KMT2AGAATP53ALDH1A1 | |
| SCHEMBL31079959 | 0.81 | MEN1 (0.45) | MEN1KMT2ACMA1AHRPIM1 | |
| SCHEMBL1613237 | 0.80 | MEN1 (0.42) | MEN1KMT2ACMA1AHRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713096-A1 | CDK INHIBITOR COMPOUNDS | Aleksia Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |
| WO-2024238574-A1 | CDK INHIBITOR COMPOUNDS | ALEKSIA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |