Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451886 | 0.83 | ALDH1A1 (0.41) | ALDH1A1ALOX15TRPA1 | |
| SCHEMBL21332863 | 0.82 | TSHR (0.39) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5520918 | 0.81 | HSD17B10 (0.43) | ALDH1A1ALOX15TDP1HSD17B10 | |
| 3-Methylbutanol SCHEMBL5545959 | 0.80 | TSHR (0.40) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL14438151 | 0.80 | USP2 (0.38) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10281930 | 0.79 | HSD17B10 (0.38) | ALDH1A1ALOX15TDP1HSD17B10 | |
| SCHEMBL12890311 | 0.78 | TSHR (0.52) | ALDH1A1HSD17B10 | |
| SCHEMBL11445081 | 0.78 | TSHR (0.52) | ALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL130769 | 0.78 | TSHR (0.42) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL23250874 | 0.77 | TSHR (0.39) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083378-A2 | MIXTURES COMPRISING GRAPHITE AND GRAPHENE MATERIALS AND PRODUCTS AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100176351-A1 | MIXTURES COMPRISING GRAPHITE AND GRAPHENE MATERIALS AND PRODUCTS AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-07-15 | — | — | US | disclosed |
| US-20060167001-A1 | Pyridazinone-derivatives as pde4 inhibitors | ALTANA PHARMA AG (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060094710-A1 | Piperidine-pyridazones and phthalazones as pde4 inhibitors | ALTANA PHARMA AG (DE) | 2006-05-04 | — | — | US | disclosed |
| EP-1086096-B1 | BENZAMIDES WITH TETRAHYDROFURANYLOXY SUBSTITUTENTS AS PHOSPHODIESTERASE 4 INHIBITORS | ALTANA PHARMA AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1086096-A1 | BENZAMIDES WITH TETRAHYDROFURANYLOXY SUBSTITUTENTS AS PHOSPHODIESTERASE 4 INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| EP-1075476-A1 | NOVEL BENZIMIDAZOLES AND BENZOXAZOLES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999064414-A1 | BENZAMIDES WITH TETRAHYDROFURANYLOXY SUBSTITUTENTS AS PHOSPHODIESTERASE 4 INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999057115-A1 | NOVEL BENZIMIDAZOLES AND BENZOXAZOLES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094710-A1 | Piperidine-pyridazones and phthalazones as pde4 inhibitors | PDE4A, PDE4B, PDE3A | ALDH1A1 88/4885ALOX15 4335/4885CA12 4223/4885 |
| US-20060167001-A1 | Pyridazinone-derivatives as pde4 inhibitors | PDE4A, PDE3A, PDE4B | ALDH1A1 470/4885ALOX15 3468/4885CA12 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.