Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943244 | 1.00 | BRD4 (0.51) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL22943441 | 0.90 | BRD4 (0.53) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL29577865 | 0.90 | BRD4 (0.53) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL22944602 | 0.89 | BRD4 (0.50) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL29579110 | 0.89 | BRD4 (0.50) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL22944540 | 0.89 | JAK2 (0.50) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL29578270 | 0.89 | BRD4 (0.51) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL29578727 | 0.89 | JAK2 (0.50) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL22944616 | 0.89 | BRD4 (0.51) | BRD4KDM4EPKMIDO1TDO2 | |
| SCHEMBL22944576 | 0.88 | BRD4 (0.49) | BRD4KDM4EPKMIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728949-B | Heterocyclic compounds as kinase inhibitors and uses thereof | 曙方医药 | 2024-11-12 | — | — | CN | disclosed |