Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21015191 | 0.89 | ADORA3 (0.53) | ADORA3ADORA1ADORA2BHTR2CHTR2B | |
| SCHEMBL31228206 | 0.83 | ADORA2A (0.38) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL21015427 | 0.82 | ADORA3 (0.52) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL31140757 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL30284387 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL23927944 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL25382883 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL30901676 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1ADORA2BPGK1PGK2 | |
| SCHEMBL31228200 | 0.81 | NT5E (0.37) | ADORA3ADORA1ADORA2BHTR2CHTR2B | |
| SCHEMBL28678580 | 0.78 | ADORA3 (0.55) | ADORA3ADORA1ADORA2BPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | claimed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | claimed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |