Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 7/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.44 |
| ▸ | ADK | P55263 | 3/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228235 | 1.00 | PRMT5 (0.44) | PRMT5WDR77ADKMETTL3METTL14 | |
| SCHEMBL31228076 | 0.87 | ADK (0.41) | PRMT5WDR77ADK | |
| SCHEMBL31228185 | 0.86 | PRMT5 (0.51) | PRMT5WDR77 | |
| SCHEMBL31228198 | 0.86 | ADK (0.57) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL31228232 | 0.83 | SLC29A1 (0.44) | PRMT5WDR77 | |
| SCHEMBL31228186 | 0.83 | PRMT5 (0.46) | PRMT5WDR77ADK | |
| SCHEMBL31228151 | 0.83 | PRMT5 (0.40) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL31228126 | 0.82 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL31228460 | 0.82 | HDAC6 (0.36) | PRMT5WDR77ADK | |
| SCHEMBL31228497 | 0.78 | ADK (0.33) | PRMT5WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | claimed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | claimed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |