Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16647595 | 0.91 | ADORA2A (0.39) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL31228203 | 0.90 | ADORA2A (0.39) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL31228206 | 0.89 | ADORA2A (0.38) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL31228544 | 0.88 | ADORA2A (0.39) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL16647433 | 0.86 | ADORA2A (0.35) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL16373866 | 0.85 | ADORA2A (0.36) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL17863693 | 0.84 | ADORA2A (0.38) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL22474872 | 0.83 | ADORA2A (0.37) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL20754490 | 0.83 | ADORA2A (0.40) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 | |
| SCHEMBL18672103 | 0.83 | ADORA2A (0.40) | ADORA2AADORA3ADORA1ADORA2BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | claimed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | claimed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |