SCHEMBL31228207

SCHEMBL31228207

[2H]c1cc([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@H]2O)n2ncnc(N)c12

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLRMT O00411 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16708504 0.91 POLRMT (0.68) POLRMT
SCHEMBL19778886 0.91 POLRMT (0.68) POLRMT
SCHEMBL13486311 0.83 POLRMT (0.61) POLRMT
SCHEMBL20756076 0.82 POLRMT (0.57) POLRMT
SCHEMBL16698968 0.82 POLRMT (0.57) POLRMT
SCHEMBL16708549 0.80 POLRMT (0.52) POLRMT
SCHEMBL23959993 0.79 POLRMT (0.48) POLRMT
SCHEMBL13486314 0.78 POLRMT (0.55) POLRMT
SCHEMBL20960067 0.75 POLRMT (0.54) POLRMT
SCHEMBL30618156 0.74 POLRMT (0.51) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO disclosed