SCHEMBL31228277

SCHEMBL31228277

[O-][n+]1ccc2cc(F)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CYP2A6 P11509 1/20 0.46
TDO2 P48775 1/20 0.36
BACE1 P56817 1/20 0.34
AHR P35869 2/20 0.32
CYP2D6 P10635 2/20 0.32
CCR3 P51677 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2775348 1.00 CYP1A2 (0.46) CYP1A2CYP2A6TDO2BACE1AHR
SCHEMBL18733501 0.92 CYP1A2 (0.46) CYP1A2CYP2A6TDO2BACE1AHR
SCHEMBL31556379 0.75 CYP2A6 (0.46) CYP1A2CYP2A6BACE1AHRL3MBTL1
SCHEMBL1536308 0.75 CYP2A6 (0.46) CYP1A2CYP2A6BACE1AHRL3MBTL1
SCHEMBL16637560 0.75 CYP2A6 (0.46) CYP2A6AHR
SCHEMBL3698199 0.75 CYP1A2 (0.54) CYP1A2CYP2A6BACE1
SCHEMBL6562601 0.74 CYP1A2 (0.77) CYP1A2CYP2A6BACE1AHRL3MBTL1
SCHEMBL30366405 0.74 CYP1A2 (0.77) CYP1A2CYP2A6BACE1AHRL3MBTL1
SCHEMBL1412043 0.73 CYP2A6 (0.52) CYP1A2CYP2A6L3MBTL1ACHE
Hydrochloric Acid SCHEMBL6435272 0.73 CYP2A6 (0.45) CYP2A6BACE1AHRL3MBTL1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024226875-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR ATTENUATION OF MAMMALIAN TRANSLATION OF C-MYC OR N-MYC PROTEINS OF THE MYC PROTO-ONCOGENE FAMILY OF BHLH TRANSCRIPTION FACTORS INITIAL THERAPEUTICS, INC. (US) 2024-10-31 WO disclosed