SCHEMBL31228366

SCHEMBL31228366

C[C@]1(O)[C@H](c2ccc3c(N)ncnn23)O[C@@](CO)(N=[N+]=[N-])[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLRMT O00411 1/20 0.51
DOT1L Q8TEK3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16708504 0.82 POLRMT (0.68) POLRMTDOT1L
SCHEMBL19778886 0.82 POLRMT (0.68) POLRMTDOT1L
SCHEMBL13486311 0.82 POLRMT (0.61) POLRMTDOT1L
SCHEMBL25402822 0.81 POLRMT (0.51) POLRMTDOT1L
SCHEMBL30618156 0.81 POLRMT (0.51) POLRMTDOT1L
SCHEMBL13471155 0.81 POLRMT (0.49) POLRMTDOT1L
SCHEMBL13471043 0.81 POLRMT (0.49) POLRMTDOT1L
SCHEMBL20756076 0.80 POLRMT (0.57) POLRMTDOT1L
SCHEMBL16698968 0.80 POLRMT (0.57) POLRMTDOT1L
SCHEMBL13486314 0.80 POLRMT (0.55) POLRMTDOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO disclosed