Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB1 | Q9Y478 | 17/20 | 0.78 |
| ▸ | PRKAG1 | P54619 | 16/20 | 0.78 |
| ▸ | PRKAA2 | P54646 | 11/20 | 0.78 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.78 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.57 |
| ▸ | TFDP2 | Q14188 | 1/20 | 0.57 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.57 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31176342 | 0.96 | PRKAB1 (0.75) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176506 | 0.95 | PRKAB1 (0.74) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176358 | 0.94 | PRKAB1 (0.73) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31228640 | 0.94 | PRKAB1 (0.73) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176387 | 0.94 | PRKAB1 (0.73) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176330 | 0.93 | PRKAB1 (0.71) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176429 | 0.93 | PRKAB1 (0.80) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176388 | 0.93 | PRKAB1 (0.77) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176303 | 0.89 | PRKAB1 (0.72) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL31176385 | 0.89 | PRKAB1 (0.72) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233280-A1 | HETEROBIFUNCTIONAL SMALL MOLECULES THAT DEUBIQUITINYLATE AND STABILIZE TARGET PROTEINS BY RECRUITING USP7 | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2024-11-14 | — | — | WO | disclosed |