SCHEMBL31228648

SCHEMBL31228648

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
VIPR2 P41587 6/20 0.43
VIPR1 P32241 3/20 0.43
NPY4R P50391 5/20 0.43
NPY1R P25929 4/20 0.43
NPY2R P49146 4/20 0.43
NPY5R Q15761 4/20 0.43
CTSD P07339 1/20 0.43
BACE1 P56817 1/20 0.43
F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29422990 1.00 VIPR2 (0.43) VIPR2VIPR1NPY4RNPY1RNPY2R
SCHEMBL30826388 0.96 BACE1 (0.46) NPY4RNPY1RNPY2RNPY5RCTSD
SCHEMBL29500481 0.94 VIPR2 (0.49) VIPR2VIPR1CTSDBACE1
SCHEMBL29406555 0.94 VIPR2 (0.49) VIPR2VIPR1CTSDBACE1
SCHEMBL30378956 0.92 VIPR2 (0.45) VIPR2VIPR1NPY4RNPY1RNPY2R
SCHEMBL10943030 0.92 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RCTSD
SCHEMBL30680480 0.92 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RCTSD
SCHEMBL31756878 0.90 NPY4R (0.45) VIPR2VIPR1NPY4RNPY1RNPY2R
SCHEMBL31188463 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RCTSD
SCHEMBL30512671 0.90 ENPEP (0.50) VIPR2VIPR1BACE1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119235-A Acylated glucagon analogues 西兰制药公司 2024-12-13 CN disclosed
CN-119119233-A Acylated glucagon analogues 西兰制药公司 2024-12-13 CN disclosed
CN-119119234-A Acylated glucagon analogues 西兰制药公司 2024-12-13 CN disclosed
CN-105745222-B Acylated glucagon analogues 西兰制药公司 2024-09-13 CN disclosed