Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228676 | 1.00 | AOC3 (0.37) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL23209157 | 0.80 | AOC3 (0.47) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL18704243 | 0.80 | AOC3 (0.47) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL4619082 | 0.75 | CNR1 (0.43) | ESR1ESR2TSHRMAPK1HIF1A | |
| SCHEMBL11078905 | 0.75 | ESR1 (0.48) | ESR1ESR2TSHRMAPK1HIF1A | |
| SCHEMBL31621800 | 0.74 | AOC3 (0.40) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL390530 | 0.72 | ADRB2 (0.45) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL25343596 | 0.72 | ADRB2 (0.45) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL18376570 | 0.72 | ADRB2 (0.45) | AOC3ESR1ESR2TSHRMAPK1 | |
| SCHEMBL31288582 | 0.71 | AOC3 (0.42) | AOC3TSHRMAPK1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118922185-A | N3-substituted uracil compounds as TRPA1 inhibitors | D·E·萧尔研究有限责任公司 | 2024-11-08 | — | — | CN | disclosed |