Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833718 | 0.98 | GAA (0.52) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL31144588 | 0.98 | GAA (0.52) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL17678098 | 0.97 | GAA (0.47) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL17673642 | 0.93 | HSD17B10 (0.42) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL2943825 | 0.89 | GAA (0.58) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL15288726 | 0.87 | GAA (0.61) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL19689454 | 0.87 | PIK3CD (0.42) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL15825750 | 0.86 | PRKCI (0.53) | GAAHSD17B10HCAR1HTTDRD2 | |
| SCHEMBL15206029 | 0.86 | HCAR1 (0.50) | GAAHSD17B10HCAR1ALDH1A1HPGD | |
| SCHEMBL15205616 | 0.86 | DDB1 (0.43) | GAAHSD17B10HCAR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724899-A | 2 (1H) -quinoxalinone compounds, pharmaceutical compositions and uses thereof | 中国药科大学 | 2024-10-01 | — | — | CN | disclosed |