Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961037 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53RXFP1MAPTMEN1 | |
| SCHEMBL30048544 | 0.75 | MAPT (0.39) | SMN1; SMN2MAPT | |
| SCHEMBL10844990 | 0.73 | RXFP1 (0.65) | SMN1; SMN2RXFP1THRBMAPTALDH1A1 | |
| SCHEMBL10851150 | 0.72 | KDM4E (0.51) | TP53RXFP1ALDH1A1MEN1POLB | |
| SCHEMBL23601061 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2RXFP1THRBMAPTALDH1A1 | |
| SCHEMBL23601890 | 0.69 | TP53 (0.39) | SMN1; SMN2TP53RXFP1THRBMAPT | |
| SCHEMBL23578049 | 0.68 | ABCG2 (0.42) | SMN1; SMN2 | |
| SCHEMBL30920847 | 0.68 | KDM4E (0.39) | SMN1; SMN2TP53MAPTMEN1POLB | |
| SCHEMBL30978986 | 0.68 | TOP2A (0.39) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL30013412 | 0.67 | CYP11B2 (0.38) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |